Nystatin
was discovered in the New York State Health Laboratory is a antimycotic polyene
antibiotic obtained from Streptomyces noursei. It is structurally similar toamphotericin B and has the same mechanism of action.
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Nystatin Vaginal Tablet |
Nystatin is
20-(4-amino-3,5-dihydroxy-6-methyl-oxan-2-yl)oxy-4,22,24,28,29,32,34,36-octahydroxy-2,3,5-trimethyl-26,38-dioxo-1-oxacyclooctatriaconta-6,8,12,14,16,18-hexaene-23-carboxylicacid.Its
molecular formula is C47H75NO17. Nystatin is a yellow to light tan powder. It
is freely soluble in dimethylformamide, slightly sparingly soluble in methyl
alcohol, n-propyl alcohol and n-butyl alcohol, practically insoluble in
alcohol, chloroform, and ether and insoluble in water.
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