Drug delivery
systems offer the potential to improve the therapeutic index of
chemotherapeutic agents via targeting the antitumor drug to its desired site of
action, and hence, increasing the drug concentration
in cancer cells and decreasing its concentration in healthy cells.
Several
nano-sized drug carriers, such as nanoparticles, liposomes, micells and
polymer-drug conjugates, have been investigated in order to minimize side
effects of anticancer drugs and enhance the antitumoral drug efficacy in cancer
therapy.
Drug delivery
systems offer the potential to improve the therapeutic index of
chemotherapeutic agents via targeting the antitumor drug to its desired site of
action, and hence, increasing the drug concentration in cancer cells and
decreasing its concentration in healthy cells.
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