Recent Trends in Pharmaceutical Biotechnology

The foundations of pharmaceutical biotechnology mainly lie in the capability of plants, microorganism and animals to produce low and high molecular weight compounds useful as therapeutics.

Although molecules from plants and microorganisms are preferred extraction from plant biomass needs tedious downstream processing while in case of microorganisms it is easy with fewer amounts of impurities. Pharmaceutical biotechnology is poised to flourish for the last 4-6 decades with the advent of recombinant DNA technology and metabolic engineering supported by the well-developed bioprocess technology.

Large scale production and cost effectiveness and affordability could be achieved by way of synergising all these technologies.

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uinoa: Nutritional Aspects

Cereals play an important role in human nutrition, contributing approximately to half the energy and protein intake of the world’s population, with wheat, corn, rice, barley, oats, rye and sorghum being the most important.

Grapes in addition to these cereals, most commonly used in human and animal nutrition, other grains, such as quinoa, amaranth, buckwheat, chia and flaxseed, have been studied in recent years because they present themselves as an excellent source of energy and protein with high nutritional value, besides fibers, lipids, vitamins and minerals.

Quinoa (Chenopodium quinoa Willd.) is a plant belonging to the family Amaranthaceae, native to the Andean regions being adaptable to different types of soil and climatic conditions, Its composition has aroused the attention of the scientific community for its high nutritional value

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Gas Chromatography-Mass Spectrometry and Infra-Red Studies of Bioactive Phytoorganic Components of Combretum dolichopentalum Leaves

Plants are used as a source for many potent drugs, as plants synthesize lower molecular weight organic compounds which possess various biological activities.

A large number of medicinal plants and their purified constituents have shown therapeutic activities, and have proved as safe and effective therapeutic agents.

Many plant species have been used in folklore medicine to treat various ailments. The development of pharmaceuticals begins with identification of active principles, detailed biological assays and dosage formulations followed by clinical studies to establish safety, efficacy and pharmacokinetic profile of the new drug.

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Families that Live with Disorders Related to Substances and Addiction

The study of the importance of the family to understand people’s conflicts and suffering originated with the branch of psychology that focuses on family relations. Starting in the 1960s, the family was definitely included in clinical practice with the advent of the Family Therapy systemic models (COSTA, 2010).

Drug Addiction

The core premise of this approach is that the family is a living and open system under constant transformation. It is known that changes occur in the family according to the transformations in the society that comprises it. Thus, family composition is often diverse and is liable to have several arrangements. However, despite the transformations in family configurations, its foreground role remains unaltered. The family is the basis of personal development and the matrix of models and references, i.e., the foundation that manages to support its members. It is also the primary source of socialization and bonding. The study of the importance of the family to understand people’s conflicts and suffering originated with the branch of psychology that focuses on family relations. Read more>>>>>>

Biochemical Effects of Chamomile Oil on Inflammatory Biomarkers in Gastroenteritis

Acute gastroenteritis is a major health problem in hospital care and represents a major cause of morbidity and mortality worldwide especially indeveloping countries.

Chamomile Oil

Acute gastroenteritis is a clinical syndrome refers to inflammation of the lining of both the stomach and small intestines caused by a variety of viral, bacterial, and parasitic enteropathogens. Viruses that cause gastroenteritis include rotavirus, norovirus, adenovirus and astrovirus while the most common types of bacteria causing gastroenteritis are Salmonella, Shigella, Escherichia coli, and Campylobacter. When food contaminated with bacteria and remains at room temperature for many hours, the bacteria can multiply and increase the risk of infection. A number of protozoa can cause gastroenteritis, including Giardia lamblia, Cryptosporidium and Entamoeba histolytica. Poisoning with heavy metals can cause gastroenteritis e.g., arsenic and cadmium; also, seafood, e.g., ciguatera, scombroid and toxic encephalopathic shellfish poisoning. Read more>>>>>>

Delirium, The Geriatrics Ward Challenge

Delirium or acute confusion state is a medical emergency, characterized by altered mental status with fluctuating deficits in attention and cognition.

It’s an important cause of morbidity and mortality. Even though most of the causes are secondary to medical conditions and after they are solved, the delirium disappear, there are cases that it can persist for weeks and months.

Many risk factors are known, such as polypharmacy, restraint use, multiple illness, frailty, advanced age. Instruments like CAM (Confusion Assessment Method) can be useful to diagnose and non-pharmacological measures with low-dose antipsychotic drugs can be helpful in its resolution.

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Isolation and Identification of Multi Drug Resistant Efflux Pump Protein from Klebsiella pneumoniae

Efflux pump in bacteria contribute to intrinsic resistance to a wide variety range of antibiotic andoften have a broad substrate range due to the lack of new antibacterial agents.

Klebsiella pneumoniae

There is considerable interest in restoring the activities of older antibiotics by inhibiting the action of efflux pump and there being a usual area of active drug development by pharmaceutical companies, but the fact is that little is known about the interaction of such inhibitors with the bacterium. The addition of combinatorial drugs to the existing antibiotics can thereby enhance the activity and restore its effective use in treatment regimens. Read more>>>>>>>>